Autoantibody Diversity Is Augmented in Women with Breast Cancer and Is Related to the Stage of the Disease.

Breast cancer (BC) is the most frequent malignant neoplasia and leading cause of cancer mortality for women. A timely diagnosis of BC is crucial to ensure the best chances of survival. Among the various screening tools for BC, antibodies directed towards self-antigens or tumor-associated antigens (autoantibodies) have emerged as an alternative to image-based screening modalities. However, little attention has been paid to the global diversity of autoantibodies. This work aimed to analyze the diversity of autoantibodies reactive to antigens expressed by the BC cell line T47D in the sera of Mexican women with BC, benign breast pathology (BBP), or without breast pathology (WBP). We found that the diversity of antibodies in the sera was higher in the BC and BBP groups than in the WBP group. Likewise, the diversity changed with the progression of BC. Our results show and measure the complexity of the antibody response in breast health and disease.

Metástasis Pancreática Metacrónica de un Carcinoma de Células Renales. Reporte de un Caso / Metachronic Pancreatic Metastasis of a Renal Cell Carcinoma. Case Report

El carcinoma de células renales (CCR) a nivel mundial presenta una incidencia de 431.288 casos anuales, causando 179.368 muertes en 2020. Sin embargo, a pesar de su incidencia, el desarrollo de metástasis pancreática (MP) de un RCC es un hecho inusual. El objetivo de este manuscrito fue reportar el caso de una paciente con una MP metacrónica de un CCR. Se trata de una paciente de 56 años, sexo femenino, nefrectomizada derecha hace 132 meses por un CCR, en adyuvancia con inmunoterapia. En un control imagenológico de rutina, se le pesquisó una lesión de aspecto tumoral en el cuerpo y cola del páncreas. Se intervino quirúrgicamente, realizándose una pancreatectomía córporo-caudal con preservación esplénica. Evolucionó de forma satisfactoria, sin complicaciones, siendo dada de alta al 4º día de su cirugía. El informe del estudio de la pieza operatoria con estudio inmunohistoquímico concluyó que se trataba de una MP de CCR. La paciente se encuentra en buenas condiciones generales y reinició quimioterapia con anticuerpos monoclonales. El seguimiento frecuente y prolongado de pacientes con antecedentes de CCR, facilita un diagnóstico y tratamiento oportuno de MP facilitando el mejor pronóstico de los pacientes, con tasas más altas de supervivencia.

SUMMARY: Renal cell carcinoma (RCC) worldwide has an incidence of 431,288 cases per year, causing 179,368 deaths in 2020. However, despite its incidence, the development of pancreatic metastasis (MP) from RCC is unusual. The aim of this manuscript was to report the case of a patient with a PM of a RCC. This is a 56-year-old female patient, underwent right nephrectomy 132 months earlier for RCC. While she was in adjuvant immunotherapy, in a routine imaging control, it was found a tumor lesion in the body and the tail of the pancreas. So, she underwent surgery, performing a corpora-caudal pancreatectomy with splenic preservation. Postoperative evolution was correct, without complications, and she was discharged on the 4th day after surgery. The report of the study of the surgical piece with an immunohistochemical study included, conclusive of PM of RCC. Currently, the patient is in good general condition and restarted chemotherapy with monoclonal antibodies. Frequent and prolonged follow-up of patients with a history of RCC facilitates timely diag- nosis and treatment of PM, facilitating the best prognosis for patients, with higher survival rates.

Stress symptoms and positive coping during coronavirus disease 2019: The need to look at health from a gender perspective.

BACKGROUND: The emergency derived from coronavirus disease 2019 (COVID-19) has taught us important lessons in public and environmental health, particularly in the alarming numbers of existing noncommunicable diseases. However, one aspect to which little attention has been paid during the pandemic is mental health and its relationship with the gender perspective, in spite of gender being a determinant associated with health. In contrast, regarding health, few schemes and theories consider health from a positive and comprehensive perspective. METHODS: This study was designed to examine the symptoms of stress and positive coping from a gender perspective. For this, the Stress Symptomatology Inventory, the Positive Coping to Life Scale and a general data questionnaire were applied to 665 individuals underwent the severe acute respiratory syndrome coronavirus 2 test at the Center for Health Studies and Services of the Universidad Veracruzana from July 2020 to November 2021. FINDINGS: We found that women presented more stress symptoms and less positive coping in the factor of positive self-regulation of adverse situations and the factors of self-determination and positive self-regulation of important situations. Moreover, significant differences in the associations of these variables were observed between men and women. CONCLUSIONS: Therefore, the needs of women must be considered in the approach to the emergency department due to COVID-19 and in general in the health-disease process; therefore, not considering a gender approach will continue to deepen inequalities between sexes.

Psychological suppressive profile and autoantibodies variability in women living with breast cancer: A prospective cross-sectional study.

Breast cancer (BC) is a leading cause of women's morbimortality worldwide. Unfortunately, attempts to predict women's susceptibility to developing BC well before it becomes symptomatic, based on their genetic, family, and reproductive background have proved unsatisfactory. Here we analyze the matching of personality traits and protein serum profiles to predict women's susceptibility to developing cancer. We conducted a prospective study among 150 women (aged 18-70 years), who were distributed into three groups (n = 50): women without breast pathology and women diagnosed with BC or benign breast pathology. Psychological data were obtained through standardized psychological tests and serum protein samples were analyzed through semiquantitative protein immunoblotting. The matching for psychological and immunological profiles was constructed from these data using a mathematical generalized linear model.The model predicted that women who have stronger associations between high-intensity stress responses, emotional containment, and an increased number and reduced variability of serum proteins (detected by IgG autoantibodies) have the greatest susceptibility to develop BC before the disease has manifested clinically. Hence, the present study endorses the possibility of using psychological and biochemical tests in combination to increase the possibility of identifying women at risk of developing BC before the disease shows clinical manifestations. A longitudinal study must be instrumented to test the prediction ability of the instrument in real scenarios. Trial registration: Committee of Ethical Research of the Hospital General de México "Dr. Eduardo Liceaga," Ministry of Health (DI/12/111/03/064).

Your health is in your mouth: A comprehensive view to promote general wellness.

Background: Even though various studies recognize the importance of the oral cavity to have general health, in multidisciplinary professional practice it is almost always excluded and on an individual basis, very commonly neglected. Oral diseases are preventable, still, they are highly prevalent. Although some studies consider oral health within integral health, currently, there is no model in which the mouth is integrated within other levels for the achievement of well-being. The objective of this article was to review the importance of oral health and its connection with well-being and, based on these findings, propose a complex and comprehensive perspective for approach and care. Methods: The databases MEDLINE, PubMed, and Google Scholar were revised for randomized controlled trials and reviews that included search terms related to oral health and its relationship with the general health in its different levels (physical, psychological, social and environmental). Results: The review shows that oral health is critical, as the teeth and mouth are not only an integral part of the body, but also, they also support and enable essential human functions. That is, oral health has a multidimensional nature, as it includes the physical, psychological, social, and environmental domains that are essential for overall health and well-being. Likewise, the mouth is the psychological seat of the first physiological needs and emotional gratifications, with it we take a taste of the world around us. Thus, the mouth plays an important role in the feeling of unity and in the constitution of the self. Based on these results we propose an integrative model in which the mouth is the first step for well-being and from this integrative model we build a multidisciplinary approach which could be used in the clinical practice for the promotion of oral care and general health. Conclusion: The effort on the part of oral health professionals is essential for people's well-being and must be integrated as part of health promotion. Dental treatments alone cannot solve this problem, it requires a comprehensive and approach in which the bio-psychological, behavioral, and socio-environmental determinants are included to face this global oral health challenge. That is, without a comprehensive and multidisciplinary approach to medical science that includes dental and oral health, our public policies cannot provide the best answers to health promotion, disease prevention, early detection, and treatment.

Positive education in college students: the effects of the "self-knowledge and soul care" workshop on the emotions and character strengths / Educación positiva en estudiantes universitarios: efectos del taller "autoconocimiento y cuidado del alma" sobre las emociones y fortalezas del carácter

Objective: most healthy and unhealthy behaviors are acquired or consolidated during youth, thus a good investment in the future of any nation, should be to promote the development of young people, incorporating them into projects and programs that aspire to increase their subjective wellbeing and personal health. The Psycho-Educational Intervention (PEI) presented here has been shown to have effects on the health and wellbeing of students as well as on their academic performance. However, its effects on strength of character, emotional balance and emotional intelligence are unknown. Materials and methods: in this paper it was shows the effects of this PEI on positive education in a group of 18 students through three questionnaires: VIA-240, PANAS-20 and PIEMO. To estimate the effects of the PEI, a comparison was made between the scores obtained on the three questionnaires before and after the PEI sessions.Results: the results show that not only did character strengths, positive affect and emotional intelligence improve with PEI, but that also the character strengths and the emotional bearings arranged in a network topography changed with intervention. Also, there were some changes in the most connected nodes of the network. Conclusions: these results show that PEI improved the previous reported variables, they also show the way in which the balance of the positive and negative affects, the development of emotional intelligence and the enhancement of character strengths give access to the three pillars of positive psychology..(Au)

Objetivo: las conductas más saludables y no saludables se consolidan durante la juventud, por lo que una buena inversión de futuro de cualquier nación, debe ser promover su desarrollo, incorporándolos en proyectos que aspiren a incrementar su bienestar subjetivo y su salud. Se ha demostrado que la Intervención Psicoeducativa (IPE) que aquí se presenta tiene efectos en la salud y el bienestar de los estudiantes, así como en su rendimiento académico. Sin embargo, se desconocen sus efectos sobre las fortalezas de carácter, el equilibrio emocional y la inteligencia emocional. Materiales y métodos: en este trabajo se muestran los efectos de esta PEI en la educación positiva en un grupo de 18 estudiantes a través de tres cuestionarios: VIA- 240, PANAS-20 y PIEMO. Para su estimación, se realizó una comparación entre las puntuaciones obtenidas en los tres cuestionarios antes y después de las sesiones de la PEI. Resultados: los resultados muestran que no solo mejoraron las variables analizadas, sino que también las fortalezas del carácter y las emociones que están dispuestos en una topografía de red, cambiaron con la intervención. Además, hubo algunos cambios en los nodos más conectados de la red. Conclusiones: estos resultados muestran que la PEI mejoró las variables reportadas anteriormente, también muestran la forma en que el balance de los afectos positivos y negativos, el desarrollo de la inteligencia emocional y la potenciación de las fortalezas del carácter dan acceso a los tres pilares de la psicología positiva..(Au)

Potencial del índice de masa corporal como indicador de grasa corporal en jóvenes / Potential for body mass index as a tool to estimate body fat in young people

Objetivo: Determinar el indicador antropométrico que presenta mayor fuerza de asociación con el porcentaje de grasa corporal y la autorregulación de alimentación y actividad física en jóvenes estudiantes universitarios, para su uso por personal de enfermería en atención primaria. Método: Se realizó un estudio transversal en 3.869 estudiantes universitarios mexicanos, de los cuales el 53,9% fueron mujeres. Se siguieron procedimientos estándar para la antropometría incluyendo peso, talla y circunferencia de cintura. Con estos datos se calcularon índice de masa corporal (IMC), A Body Shape Index, índice cintura-talla, Body roundness index y Conicity index. Se aplicaron la Escala de autorregulación de hábitos alimentarios y la Escala de autorregulación de actividad física. Se estimaron medias con desviación estándar, porcentajes y coeficientes de correlación de Pearson. Resultados: El grupo de hombres presentó prevalencia superior de exceso de peso en comparación con las mujeres. Se encontraron correlaciones inversas entre la mayoría de los índices antropométricos y la autorregulación de hábitos alimentarios y de actividad física. Sin embargo, en todos los casos las correlaciones fueron bajas. El porcentaje de grasa corporal tuvo una asociación media con Conicity index y fuerte con IMC, circunferencia de cintura, índice cintura-talla y Body roundness index, siendo el IMC el que presentó el coeficiente de correlación más fuerte. Conclusiones: De los indicadores analizados, el IMC muestra la fuerza de asociación más fuerte con el porcentaje de grasa corporal en estudiantes universitarios, por lo que se sugiere mantener su uso en enfermería para la determinación de obesidad por su simplicidad de estimación.(AU)

Objective: We aim to determine the anthropometric indicator that is most strongly associated with the percentage of body fat and self-regulation of eating behaviour and physical activity among young university students. Method: A cross-sectional study was conducted on 3,869 Mexican university students, of which 53.9% were women. Standard procedures for anthropometry were followed, including weight, height and waist circumference. This data was used for calculating Body Mass Index (BMI), A Body Shape Index, waist-to-height ratio, Body Roundness Index and Conicity index. The self-regulation of eating habits scale and the self-regulation of physical activity scale were used. Mean with standard deviation, percentages and Pearson correlation coefficient were estimated. Results: The group of men shown a higher prevalence of excess weight compared to the women. Inverse correlations between most anthropometric indices and self-regulation of eating behaviour and physical activity were found. However, in all cases the correlations were weak. The percentage of fat had a medium frequency of association with Conicity index and high with BMI, waist circumference, waist-to-height ratio and Body Roundness Index, where the BMI showed the highest correlation coefficient. Conclusions: The BMI shows the highest magnitude of association with percentage of body fat in university students among the indicators analysed. Therefore it is suggested that nurses use BMI to determine obesity because it is easy to calculate.(AU)

Las ferias como medio para la promoción de la salud en la comunidad universitaria: pasos hacia una educación positiva / Fairs as a means of promoting health in the university community: steps towards a positive education

Objetivo: la promoción de la salud en términos positivos y de bienestar, implica concebirla como el proceso en el que la comunidad aumenta el control sobre su salud, y la mejora. Las universidades tienen grandes capacidades para ello; por ejemplo, en ferias de salud que rompen los esquemas tradicionales unidireccionales y pasivos de los programas de salud. El programa de salud integral de la Universidad Veracruzana (México) implementó en su primera etapa estrategias para la promoción, prevención y tratamiento de enfermedades. Más tarde incorporó una visión más integral acorde a las necesidades enmarcadas en los objetivos sostenibles y la promoción de la salud comenzó a realizarse a través de ferias. No obstante, la comunidad universitaria dudaba que su realización tuviera beneficios. Materiales y métodos: se evaluó el efecto de las ferias en la salud y bienestar percibido por los estudiantes y su entorno y se identificaron las virtudes y fortalezas de carácter, las cuales son esenciales para la vida en bienestar. Resultados: la participación de los estudiantes en las ferias de salud les aporta conocimientos y habilidades para mejorar su salud, así como para adoptar estilos de vida acordes al autocuidado y la sustentabilidad. Además, las 24 fortalezas están presentes en todos los estudiantes, aunque el autocontrol fue la fortaleza menos presente. Conclusiones: las ferias son espacios que promueven la salud, al lograr transmitir y apropiar información, al mismo tiempo que acercan y educan a diferentes públicos de manera efectiva lúdica..Au

Objective: the promotion of health in positive and well-being terms implies conceiving it as the process in which the community increases control over its health and improves it. Universities in this sense have great capacities for their promotion, for example, health fairs break the traditional unidirectional and passive schemes of health programs. The comprehensive health program of the Universidad Veracruzana, implemented in its first stage strategies for the promotion, prevention and treatment of diseases. Later, it incorporated a more comprehensive vision according to the needs framed in the sustainable objectives and the promotion of health began to be carried out through fairs. However, there was a perception in the university community that its implementation had no benefits. Materials and methods: the effect of the fairs on the perceived health and well-being of the students and their environment was evaluated, and the virtues and strengths of character, which are essential for life in well-being, were identified. Results: the participation of the students provides them with knowledge and skills to improve their health, as well as to adopt lifestyles consistent with self-care and sustainability. In addition, the 24 strengths are present in all students, although self-control was the least present strength. Conclusions: fairs are spaces that promote health, by transmitting and appropriating information, at the same time that they approach and educate different audiences in an effective playful way..Au

Potential for body mass index as a tool to estimate body fat in young people. / Potencial del índice de masa corporal como indicador de grasa corporal en jóvenes.

OBJECTIVE: We aim to determine the anthropometric indicator that is most strongly associated with the percentage of body fat and self-regulation of eating behaviour and physical activity among young university students. METHOD: A cross-sectional study was conducted on 3,869 Mexican university students, of which 53.9% were women. Standard procedures for anthropometry were followed, including weight, height and waist circumference. This data was used for calculating Body Mass Index (BMI), A Body Shape Index, waist-to-height ratio, Body Roundness Index and Conicity index. The self-regulation of eating habits scale and the self-regulation of physical activity scale were used. Mean with standard deviation, percentages and Pearson correlation coefficient were estimated. RESULTS: The group of men shown a higher prevalence of excess weight compared to the women. Inverse correlations between most anthropometric indices and self-regulation of eating behaviour and physical activity were found. However, in all cases the correlations were weak. The percentage of fat had a medium frequency of association with Conicity index and high with BMI, waist circumference, waist-to-height ratio and Body Roundness Index, where the BMI showed the highest correlation coefficient CONCLUSIONS: The BMI shows the highest magnitude of association with percentage of body fat in university students among the indicators analysed. Therefore it is suggested that nurses use BMI to determine obesity because it is easy to calculate.

Psychological factors as coping skills to attenuate the gestational stress response / Factores psicológicos como medidas de afrontamiento para modular la respuesta al estrés gestacional

OBJECTIVE: Although in the 1940s there was an important decrease in global maternal/infant mortality rates, by the 1990s these rates had become stagnant. Many strategies to decrease maternal/infant mortality had been used, which included the prevention of pregnancy complications. Several studies showed an association between these complications and the stress perceived during pregnancy. However, there are some discrepancies which challenge this association. We believe that these discrepancies are due to the lack of understanding about the pregnant stress response and consequently the ways it is measured. The aim of this study was to understand how pregnant women perceive motherhood, pregnancy stressors and the psychological factors that attenuate the stress response. MATERIALS AND METHODS: A qualitative study was conducted that explores the perception of gestational stress in 32 pregnant women who were recruited in different Health Centers. Semi-structured interviews were carried out which were conducted by the PhD student in charge of the project and each interview lasted 15-20 min. Since the interviews were audio-recorded they were transcribed and the information was then categorized according to the three issues raised in the objective (motherhood, pregnancy stressors, and psychological factors that attenuate the stress response). RESULTS AND CONCLUSIONS: We found that the gestational stress response and also its magnitude are influenced not only by how women perceive the aspects, but also and most importantly by its articulation. Likewise, results show that gestational stress is only attenuated when women perceive and cope with both the positive and negative aspects of pregnancy and motherhood

OBJETIVO: Si bien en 1940 hubo una disminución importante en las tasas globales de mortalidad materno/infantil, hacia 1990 estas tasas se estancaron. Desde entonces se han utilizado muchas estrategias para disminuir la mortalidad materno/infantil, las cuales incluyen la prevención de las complicaciones del embarazo. Varios estudios mostraron una asociación entre estas complicaciones y el estrés percibido durante el embarazo. Sin embargo, hay algunas discrepancias que desafían esta asociación. Creemos que estas discrepancias se deben al poco entendimiento que tenemos sobre la respuesta al estrés durante el embarazo y, en consecuencia, en la forma en que esta se mide. Es por ello que el objetivo de este estudio es comprender cómo las mujeres embarazadas perciben la maternidad, los estresores propios del embarazo y los factores psicológicos que modulan la respuesta al estrés. MATERIALES Y MÉTODOS: Se realizó un estudio cualitativo que explora la percepción sobre el estrés gestacional en 32 mujeres embarazadas que eran derechohabientes de los centros de salud. Para ello se realizaron entrevistas semiestructuradas, las cuales fueron realizadas por la estudiante de doctorado encargada del proyecto, y cada una tuvo una duración de 15 a 20 min. Puesto que las entrevistas fueron audiograbadas, se transcribieron y se categorizó la información de acuerdo con los 3 temas planteados en el objetivo (percepción de la maternidad, estresores propios del embarazo y factores psicológicos moduladores de estrés). RESULTADOS Y CONCLUSIONES: Encontramos que la respuesta del estrés gestacional y su magnitud son influidas no solo por la percepción que tiene la mujer de estos aspectos, sino sobre todo por su articulación. Además, los resultados muestran que el estrés gestacional solo se atenúa cuando las mujeres perciben y enfrentan tanto los aspectos positivos como los negativos del embarazo y la maternidad

Design and Psychometric Analysis of the Stressors and Modulators of Gestational Stress Inventory (SMGSI).

Gestational stress is associated with many maternal and child complications, however, this association must be taken with care, since there are studies that find inconsistent results between stress measures and maternal complications. It is believed that the lack of convergence is due to the way in which gestational stress is evaluated.The aim of the present study was to design and validate an instrument based on a bio-psycho-social model of gestational stress. The design and validation process of the inventory was divided into four phases: (a) Construction of the items bank and content validity, (b) construct validity, (c) inventory reliability and (d) convergent and discriminant validity with psychometric instruments that have been used in other investigations to evaluate gestational stress.A valid and reliable Stressors and Modulators of Gestational Stress Inventory (SMGSI) conformed by two scales was developed: (a) Gestational stressors, which is formed by two factors, the psychological stressors and social stressors with a variance of 48.5% and 51.8% and a reliability of .79 and .67, respectively; and (b) gestational stress modulators integrated by 8 items that explain 55.2% of the variance and with a reliability of .92. In conclusion, a valid and reliable tool was obtained that measures gestational stress from a bio-psycho-social perspective. This inventory allows for the identification of allostatic and pantostatic stress, making it useful as a diagnostic tool to prevent maternal and childhood complications that are associated with chronic gestational stress.

Efectividad antibacteriana de plantas medicinales utilizadas en aceites esenciales, pastas y enjuagues dentales / Antibacterial effectiveness of medicinal plants used in essential oils, pastes and dental rinses

Introducción. La herbolaria constituye el recurso más conocido y accesible para la población mexicana por lo que la OMS, reconoce su valor terapéutico. Objetivo. Determinar si existe efectividad antibacteriana de plantas medicinales utilizadas en aceites esenciales, pastas y enjuagues dentales, a través de la revisión de reportes científicos previamente publicados. Materiales y Métodos. Se realizó una búsqueda bibliográfica en: Pubmed y SciELO de artículos relacionados con las palabras clave, en inglés, publicados de marzo 2015-marzo 2020. Resultados. Del total de los artículos revisados encontramos 170 y seleccionamos 56 para el presente estudio. Conclusiones. El uso de plantas en aceites esenciales, pastas y enjuagues dentales es efectivo ante las bacterias presentes en boca debido a la presencia de compuestos polifenólicos bioactivos que poseen efectos antibacterianos.

Design and psychometric analysis of the Stressors and Modulators of Gestational Stress Inventory (SMGSI)

Gestational stress is associated with many maternal and child complications, however, this association must be taken with care, since there are studies that find inconsistent results between stress measures and maternal complications. It is believed that the lack of convergence is due to the way in which gestational stress is evaluated. The aim of the present study was to design and validate an instrument based on a bio-psycho-social model of gestational stress. The design and validation process of the inventory was divided into four phases: (a) Construction of the items bank and content validity, (b) construct validity, (c) inventory reliability and (d) convergent and discriminant validity with psychometric instruments that have been used in other investigations to evaluate gestational stress. A valid and reliable Stressors and Modulators of Gestational Stress Inventory (SMGSI) conformed by two scales was developed: (a) Gestational stressors, which is formed by two factors, the psychological stressors and social stressors with a variance of 48.5% and 51.8% and a reliability of .79 and .67, respectively; and (b) gestational stress modulators integrated by 8 items that explain 55.2% of the variance and with a reliability of .92. In conclusion, a valid and reliable tool was obtained that measures gestational stress from a bio-psycho-social perspective. This inventory allows for the identification of allostatic and pantostatic stress, making it useful as a diagnostic tool to prevent maternal and childhood complications that are associated with chronic gestational stress

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Análisis estructural de la Escala de Bienestar Psicológico de Ryff en universitarios mexicanos / Structural analysis of the Ryff’s Psychological Well-Being Scale among Mexican college students

Objetivos: realizar el análisis de la estructura interna de la versión en español de la Escala de Bienestar Psicológico de Ryff (PWBS-E) en estudiantes universitarios (n = 1700; 54.75% mujeres; Medad = 19.23) de una institución pública en Veracruz, México. Método: La estructura interna de la PWBS-E fue evaluada mediante el análisis factorial confirmatorio (CFA), el modelamiento de ecuaciones estructurales exploratorio (ESEM) y el análisis factorial exploratorio (EFA). La confiabilidad del constructo fue estimada con el coeficiente α y de las puntuaciones con el coeficiente α. Resultados: indicaron que una estructura unidimensional y breve (19 ítems) posee mayor respaldo empírico. Además, se evidenció la existencia de un factor de método asociado a ítems invertidos en los modelos multidimensionales. En cuanto a la confiabilidad, se hallaron indicadores aceptables en ambos niveles (constructo y puntuaciones). Conclusiones: se discuten los hallazgos y las implicancias prácticas de la versión breve de la PWBS-E en universitarios

Objectives: This paper aimed to analyze the internal structure of the Spanish version of the Ryff ’s psychological well-being scale (PWBS-E) among college students (n = 1700, 54.75% females, Mage = 19.23) who attend a public institution located in Veracruz, Mexico. Method: The internal structure of the PWBS-E was assessed using the confirmatory factor analysis (CFA), exploratory structural equation modeling (ESEM) and exploratory factor analysis (EFA), while the reliability of the construct was estimated with the ù coefficient and the reliability of the scores, with the α coefficient. Results: Suggested that a short and unidimensional structure (19 items) provides greater empirical support. In addition, a method factor associated with inverted items in multidimensional models was evidenced. Regarding the reliability, acceptable indicators were found in both levels (construct and scores). Conclusions: This paper addresses both the findings and practical implications of the short version of the PWBS-E among college students.

Efecto de la sinergia de los factores de riesgo para cáncer de mama en mujeres de la ciudad de Veracruz / Synergic effect of risk factors for breast cancer in women from Veracruz city

Introducción y objetivos: El cáncer de mama (CaMa) es la neoplasia más común en las mujeres. La Organización Mundial de la Salud estima que el 30% de las muertes por CaMa son debidas a factores asociados a estilos de vida. En México hay una epidemia de obesidad, que favorece la aparición de hipertensión arterial y diabetes mellitus 2. No obstante, la prevalencia y contribución clínica de esta tríada en el desarrollo del CaMa y su interacción con los factores de riesgo conocidos han sido poco estudiados. Materiales y métodos: Se analizó asociación de obesidad, la hipertensión arterial y la diabetes mellitus 2 y de los factores de riesgo para CaMa (reportados en los expedientes clínicos de mujeres con y sin diagnóstico de CaMa del Hospital N.° 71 del Instituto Mexicano del Seguro Social) y su peso proporcional, con la ausencia o presencia de diagnóstico de CaMa. Resultados: Solo los antecedentes heredofamiliares y el tabaquismo, de los factores de riesgo reconocidos para CaMa, mostraron asociación con el diagnóstico de CaMa. Tampoco las enfermedades metabólicas mostraron diferencias. No obstante, el peso proporcional de todas las variables sí mostró significación estadística en el grupo con CaMa. Conclusiones: La visión clásica de que los factores de índole clínico per se son determinantes para el desarrollo de CaMa necesita ser modificada. Es necesario realizar estudios que consideren la interrelación que guardan los factores de riesgo entre sí y otros trastornos que se han normalizado en la población

Introduction and objectives: Breast cancer (BC) is the most common neoplasm in women worldwide. The World Health Organisation estimates that 30% of deaths due to BC are associated with lifestyle factors. In Mexico there is an obesity epidemic, which favours the appearance of hypertension and diabetes mellitus type 2 (DM2). However, there have been few studies of the prevalence and clinical contribution of this triad in the development of BC and its interaction with known risk factors. Materials and methods: We analysed the association of obesity, hypertension and DM2, and risk factors for BC (reported in the clinical files of women with and without a diagnosis of BC in Hospital N.° 71 of the Mexican Institute of Social Security) and their proportional weight, with the presence or absence of a BC diagnosis. Results: Among the recognised risk factors for BC, only a hereditary family history and smoking were associated with a diagnosis of BC. Metabolic diseases showed no differences. However, the proportional weight of all the variables was statistically significant in the group with BC. Conclusions: There is a need to modify the classical view that clinical factors per se determine the development of BC. Studies are needed that analyse the interrelation between risk factors and other disorders that have become highly prevalent in the population

Dental erosion, an extraesophageal manifestation of gastroesophageal reflux disease. The experience of a center for digestive physiology in Southeastern Mexico.

BACKGROUND: Dental erosion (DE) is the loss of the hard tissues of the tooth produced by the action of gastric juice, pepsin and acid on the dental enamel, its frequency ranges from 5 to 53.41 %. In Mexico there are no reports on the frequency and possible association. OBJECTIVE: To establish the prevalence of dental erosion and its relationship to GERD. PATIENTS AND METHODS: Prospective, observational, descriptive and comparative study was conducted in 60 patients diagnosed with GERD and 60 healthy patients at the Institute of Medical and Biological Research of the Universidad Veracruzana in Veracruz city. Anthropometric characteristics, dietary habits, oral hygiene, alcohol consumption, smoking, ED index and Index of decayed/missing dental pieces/sealed and correlation between severity of ED and GERD were analyzed. RESULTS: 78.67 % of patients with GERD had ED, 23.33 % corresponded to grade 0, 41.67 % to N1, N2 and 23.33 % to 11.67 % to N3. Predominance of females (2,3:1). The mean age was 50.92 +/- 13.52 years. The severity of dental erosion was significantly related to the severity of reflux, halitosis, CPO index and poor eating habits. There was no statistically significant difference in the other variables analyzed. CONCLUSIONS: Dental erosion has a high frequency in patients with GERD and reflux characteristics are directly related to their severity and therefore should be considered as a manifestation of GERD extraesophageal.

Erosión dental, una manifestación extraesofágica de la enfermedad por reflujo gastroesofágico. Experiencia de un centro de fisiología digestiva en el sureste de México / Dental erosion, an extraesophageal manifestation of gastroesophageal reflux disease. The experience of a center for digestive physiology in Southeastern Mexico

Antecedentes: la erosión dental (ED) es la pérdida de los tejidos duros del diente producida entre otras cosas por la acción del jugo gástrico, la pepsina y el ácido sobre el esmalte dentario, su prevalencia varía entre 5 y 53,41 %. En México no existen publicaciones sobre su frecuencia y posible asociación. Objetivo: establecer la prevalencia de las erosiones dentales y su relación con la enfermedad por reflujo gastroesofágico (ERGE). Pacientes y métodos: estudio prospectivo, observacional, descriptivo y comparativo realizado en 60 pacientes con diagnóstico de ERGE y 60 sujetos sanos en el Instituto de Investigaciones Médico-Biológicas de la Universidad Veracruzana en la ciudad de Veracruz. Se analizaron las características antropométricas, hábitos alimentarios, higiene oral, consumo de alcohol, tabaquismo, índice de ED e índice de piezas dentales cariadas/perdidas/obturadas (CPO) y la correlación entre severidad de ED y la ERGE. Resultados: El 78,67 % de los pacientes con ERGE presentaron ED; el 23,33 % correspondieron al grado N0, 41,67 % al N1, 23,33 % al N2 y 11,67 % al N3. Predominó el género femenino (2,3:1). La edad promedio fue 50,92 ± 13,52 años. La gravedad de la erosión dental se relacionó significativamente con la severidad del reflujo, halitosis, índice CPO y con malos hábitos alimentarios. No hubo diferencia estadísticamente significativa en las demás variables analizadas. Conclusiones: la erosión dental tiene una alta frecuencia en pacientes con ERGE y las características del reflujo se relacionan directamente con su severidad por lo cual debe ser considerada como una manifestación extraesofágica más de la ERGE (AU)

Background: Dental erosion (DE) is the loss of the hard tissues of the tooth produced by the action of gastric juice, pepsin and acid on the dental enamel, its frequency ranges from 5 to 53.41 %. In Mexico there are no reports on the frequency and possible association. Objective: To establish the prevalence of dental erosion and its relationship to GERD. Patients and methods: Prospective, observational, descriptive and comparative study was conducted in 60 patients diagnosed with GERD and 60 healthy patients at the Institute of Medical and Biological Research of the Universidad Veracruzana in Veracruz city. Anthropometric characteristics, dietary habits, oral hygiene, alcohol consumption, smoking, ED index and Index of decayed/missing dental pieces/sealed and correlation between severity of ED and GERD were analyzed. Results: 78.67 % of patients with GERD had ED, 23.33 % corresponded to grade 0, 41.67 % to N1, N2 and 23.33 % to 11.67 % to N3. Predominance of females (2,3:1). The mean age was 50.92 ± 13.52 years. The severity of dental erosion was significantly related to the severity of reflux, halitosis, CPO index and poor eating habits. There was no statistically significant difference in the other variables analyzed. Conclusions: Dental erosion has a high frequency in patients with GERD and reflux characteristics are directly related to their severity and therefore should be considered as a manifestation of GERD extraesophageal (AU)

Desgaste dental y bruxismo / Tooth wear and bruxism

Introducción: el bruxismo es común y multifactorial que puede producir desgaste dental. Objetivo: identificar la relación de desgaste dental y bruxismo en universitarios. Material y métodos: estudio prospectivo, longitudinal, observacional, mediante examen odontológico y cuestionario directo de las molestias del bruxismo y su desgaste dental. Resultados: se encuestaron 78 universitarios con desgaste dental, 24 femeninos (30.76 por ciento) y 54 masculinos (69.23 por ciento), que perciben el desgaste dental , 65 casos (83.33 por ciento), 22 femeninos (34.92 por ciento) con edad media de 22.5 años y desviación estándar de 7.7781; 41 masculinos (65.07 por ciento) con edad media de 30.5 años y desviación estándar de 19.01918. Que no percibían hasta ese momento el desgaste dental 15 casos (19.23 por ciento), la mayoría sin conciencia de rechinar los dientes por la noche y sin molestias, pero con percepción muy clara de bruxismo en situaciones emocionales y percepción de desgaste dental en la mayoría de los casos. Para atender adecuadamente al bruxópata con desgaste dental deben tomarse en cuenta factores familiares, emocionales y alteraciones temporomaxilares que deben ser diagnosticadas y tratadas adecuadamente. Conclusiones: es muy elevado el desgaste dental en universitarios con bruxismo, hay predominio del sexo masculino con pocas molestias y percepción del desgaste